Motoharu Iwatsuru : rechercher sur Z-Library

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1

The hen's fertile egg screening test (HEST): A comparison between the acute toxicity for chick embryos and rodents of 20 drugs

Hideo Nishigori, Masashi Mizumura, Motoharu Iwatsuru

Journal:

Cell Biology and Toxicology

Année:

1992

Langue:

english

Fichier:

PDF, 579 KB

english, 1992

2

Studies on methods of particle size reduction of medicinal compounds. VI. Solvate formation of griseofulvin with benzene and dioxane.

SEKIGUCHI, KEIJI, SHIROTANI, KENICHI, KANKE, MOTOKO, FURUKAWA, HISAE, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1976

Fichier:

PDF, 1.31 MB

1976

3

Spectroscopic investigation of the molecular state of nystatin encapsulated in liposomes

Kunikazu Moribe, Kazuo Maruyama, Motoharu Iwatsuru

Journal:

International Journal of Pharmaceutics

Année:

2000

Langue:

english

Fichier:

PDF, 147 KB

english, 2000

4

Encapsulation characteristics of nystatin in liposomes: effects of cholesterol and polyethylene glycol derivatives

Kunikazu Moribe, Kazuo Maruyama, Motoharu Iwatsuru

Journal:

International Journal of Pharmaceutics

Année:

1999

Langue:

english

Fichier:

PDF, 128 KB

english, 1999

5

Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice

Osamu Ishida, Kazuo Maruyama, Katsunori Sasaki, Motoharu Iwatsuru

Journal:

International Journal of Pharmaceutics

Année:

1999

Langue:

english

Fichier:

PDF, 504 KB

english, 1999

6

Molecular localization and state of amphotericin B in PEG liposomes

Kunikazu Moribe, Kazuo Maruyama, Motoharu Iwatsuru

Journal:

International Journal of Pharmaceutics

Année:

1999

Langue:

english

Fichier:

PDF, 121 KB

english, 1999

7

Targetability and intracellular delivery of anti-BCG antibody-modified, pH-sensitive fusogenic immunoliposomes to tumor cells

Toshiro Mizoue, Toshiya Horibe, Kazuo Maruyama, Tomoko Takizawa, Motoharu Iwatsuru, Kenji Kono, Hironobu Yanagie, Fuminori Moriyasu

Journal:

International Journal of Pharmaceutics

Année:

2002

Langue:

english

Fichier:

PDF, 218 KB

english, 2002

8

Targeting Chemotherapy to Solid Tumors with Long-circulating Thermosensitive Liposomes and Local Hyperthermia

Osamu Ishida, Kazuo Maruyama, Hironobu Yanagie, Masazumi Eriguchi, Motoharu Iwatsuru

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 127 KB

english, 2000

9

Liposomes Bearing Polyethyleneglycol-Coupled Transferrin with Intracellular Targeting Property to the Solid Tumors In Vivo

Osamu Ishida, Kazuo Maruyama, Hiroyuki Tanahashi, Motoharu Iwatsuru, Katsunori Sasaki, Masazumi Eriguchi, Hironobu Yanagie

Journal:

Pharmaceutical Research

Année:

2001

Langue:

english

Fichier:

PDF, 306 KB

english, 2001

10

Enhanced Encapsulation of Amphotericin B into Liposomes by Complex Formation with Polyethylene Glycol Derivatives

Kunikazu Moribe, Eitaro Tanaka, Kazuo Maruyama, Motoharu Iwatsuru

Journal:

Pharmaceutical Research

Année:

1998

Fichier:

PDF, 583 KB

1998

11

Enhanced Delivery and Antitumor Activity of Doxorubicin Using Long-Circulating Thermosensitive Liposomes Containing Amphipathic Polyethylene Glycol in Combination with Local Hyperthermia

Sakae Unezaki, Kazuo Maruyama, Noriyuki Takahashi, Masataka Koyama, Tsutomu Yuda, Akinori Suginaka, Motoharu Iwatsuru

Journal:

Pharmaceutical Research

Année:

1994

Fichier:

PDF, 1.12 MB

1994

12

Phosphatidyl polyglycerols prolong liposome circulation in vivo

Kazuo Maruyama, Seiji Okuizumi, Osamu Ishida, Hitoshi Yamauchi, Hiroshi Kikuchi, Motoharu Iwatsuru

Journal:

International Journal of Pharmaceutics

Année:

1994

Langue:

english

Fichier:

PDF, 380 KB

english, 1994

13

Enhanced tumor targeting and improved antitumor activity of doxorubicin by long-circulating liposomes containing amphipathic poly(ethylene glycol)

Sakae Unezaki, Kazuo Maruyama, Osamu Ishida, Akinori Suginaka, Jun-ichi Hosoda, Motoharu Iwatsuru

Journal:

International Journal of Pharmaceutics

Année:

1995

Langue:

english

Fichier:

PDF, 624 KB

english, 1995

14

Targeting efficiency of PEG-immunoliposome-conjugated antibodies at PEG terminals

Kazuo Maruyama, Tomoko Takizawa, Nobuya Takahashi, Toshiaki Tagawa, Kazuhiro Nagaike, Motoharu Iwatsuru

Journal:

Advanced Drug Delivery Reviews

Année:

1997

Langue:

english

Fichier:

PDF, 881 KB

english, 1997

15

Direct measurement of the extravasation of polyethyleneglycol-coated liposomes into solid tumor tissue by in vivo fluorescence microscopy

Sakae Unezaki, Kazuo Maruyama, Jun-Ichi Hosoda, Itsuro Nagae, Yasuhisa Koyanagi, Mikiho Nakata, Osamu Ishida, Motoharu Iwatsuru, Seishi Tsuchiya

Journal:

International Journal of Pharmaceutics

Année:

1996

Langue:

english

Fichier:

PDF, 516 KB

english, 1996

16

Enhanced delivery of doxorubicin to tumor by long-circulating thermosensitive liposomes and local hyperthermia

Kazuo Maruyama, Sakae Unezaki, Noriyuki Takahashi, Motoharu Iwatsuru

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1993

Langue:

english

Fichier:

PDF, 743 KB

english, 1993

17

Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol) s conjugated at their distal terminals to monoclonal antibodies

Kazuo Maruyama, Tomoko Takizawa, Tsutomu Yuda, Stephen J Kennel, Leaf Huang, Motoharu Iwatsuru

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1995

Langue:

english

Fichier:

PDF, 678 KB

english, 1995

18

Prolonged circulation time in vivo of large unilamellar liposomes composed of distearoyl phosphatidylcholine and cholesterol containing amphipathic poly(ethylene glycol)

Kazuo Maruyama, Tsutomu Yuda, Aki Okamoto, Shuji Kojima, Akinori Suginaka, Motoharu Iwatsuru

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Année:

1992

Langue:

english

Fichier:

PDF, 923 KB

english, 1992

19

An animal model for cataract research: Cataract formation in developing chick embryo by glucocorticoid

Hideo Nishigori, Jung W. Lee, Motoharu Iwatsuru

Journal:

Experimental Eye Research

Année:

1983

Langue:

english

Fichier:

PDF, 427 KB

english, 1983

20

Preventive effect of ascorbic acid against glucocorticoid-induced cataract formation of developing chick embryos

Hideo Nishigori, Rume Hayashi, Jung W. Lee, Kazuo Maruyama, Motoharu Iwatsuru

Journal:

Experimental Eye Research

Année:

1985

Langue:

english

Fichier:

PDF, 530 KB

english, 1985

21

Elevation of glucose in ocular compartments of developing chick embryos with glucocorticoid-induced cataract

Hideo Nishigori, Jung W. Lee, Yasuhisa Yamauchi, Motoharu Iwatsuru

Journal:

Experimental Eye Research

Année:

1989

Langue:

english

Fichier:

PDF, 480 KB

english, 1989

22

Immunoliposomes bearing polyethyleneglycol-coupled Fab′ fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo

Kazuo Maruyama, Nobuya Takahashi, Toshiaki Tagawa, Kazuhiro Nagaike, Motoharu Iwatsuru

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 454 KB

english, 1997

23

Alteration of Activities of Hepatic Antioxidant Defence Enzymes in Developing Chick Embryos After Glucocorticoid Administration - A Factor to Produce Some Adverse Effects?

JUNG WHA LEE, MOTOHARU IWATSURU, HIDEO NISHIGORI

Journal:

Journal of Pharmacy and Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 522 KB

english, 1998

24

Alteration of hepatic lipidperoxide levels during cataract formation caused by glucocorticoids in developing chick embryos

Hideo Nishigori, Jung W. Lee, Yoshiko Iwamoto, Rume Hayashi, Kazuo Maruyama, Motoharu Iwatsuru

Journal:

Année:

1984

Langue:

english

Fichier:

PDF, 255 KB

english, 1984

25

Preventive effects of pyrroloquinoline quinone on formation of cataract and decline of lenticular and hepatic glutathione of developing chick embryo after glucocorticoid treatment

Hideo Nishigori, Mika Yasunaga, Masashi Mizumura, Jung W. Lee, Motoharu Iwatsuru

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 338 KB

english, 1989

26

Bioavailability of theophylline-containing poly(methyl methacrylate) microspheres in rabbits

Kazuo Maruyama, Yanee Pongpaibul, Motoharu Iwatsuru

Journal:

Journal of Controlled Release

Année:

1989

Langue:

english

Fichier:

PDF, 744 KB

english, 1989

27

Enhanced Tumor Targeting of Doxorubicin by Ganglioside GMl-bearing Long-circulating Liposomes

Unezaki, Sakae, Maruyama, Kazuo, Ishida, Osamu, Takahashi, Noriyuki, Iwatsuru, Motoharu

Journal:

Journal of Drug Targeting

Année:

1993

Langue:

english

Fichier:

PDF, 513 KB

english, 1993

28

Pigmentation of glucocorticoid-induced cataractous lenses of developing chick embryos on heating

Nishigori, Hideo, Iwatsuru, Motoharu, Hikida, Mitsushi

Journal:

Current Eye Research

Année:

1988

Langue:

english

Fichier:

PDF, 397 KB

english, 1988

29

Glucocorticoid-Induced Cataract of Developing Chick Embryo as a Screening Model for Anticataract Agents

LEE, JUNG WHA, IWATSURU, MOTOHARU, NISHIGORI, HIDEO

Journal:

Journal of Ocular Pharmacology and Therapeutics

Année:

1995

Langue:

english

Fichier:

PDF, 730 KB

english, 1995

30

Enhanced Delivery and Antitumor Effect of Doxorubicin Encapsulated in Long-Circulating Liposomes

Maruyama, Kazuo, Unezaki, Sakae, Yuda, Tsutomu, Ishida, Osamu, Takahashi, Noriyuki, Suginaka, Akinori, Huang, Leaf, Iwatsuru, Motoharu

Journal:

Journal of Liposome Research

Année:

1994

Langue:

english

Fichier:

PDF, 1.14 MB

english, 1994

31

The alteration of lipid peroxide in glucocorticoid-induced cataract of developing chick embryos and the effect of ascorbic acid

Nishigori, Hideo, Lee, Jung W., Yamauchi, Yasuhisa, Iwatsuru, Motoharu

Journal:

Current Eye Research

Année:

1986

Langue:

english

Fichier:

PDF, 346 KB

english, 1986

32

Doxorubicin Encapsulated in Long-Circulating Thermosensitive Liposomes

Maruyama, Kazuo, Iwatsuru, Motoharu

Journal:

Journal of Liposome Research

Année:

1994

Langue:

english

Fichier:

PDF, 706 KB

english, 1994

33

Preventive effect of isocitrate on glucocorticoid-induced cataract formation of developing chick embryo

Lee, Jung W., Iwatsuru, Motoharu, Nishigori, Hideo

Journal:

Current Eye Research

Année:

1991

Langue:

english

Fichier:

PDF, 622 KB

english, 1991

34

Estimation of Surface State of Poly(ethylene glycol)-Coated Liposomes Using an Aqueous Two-Phase Partitioning Technique.

MORIBE, Kunikazu, MARUYAMA, Kazuo, IWATSURU, Motoharu

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1997

Fichier:

PDF, 865 KB

1997

35

Prolongation of Liposome Circulation Time by Various Derivatives of Polyethyleneglycols.

YUDA, Tsutomu, MARUYAMA, Kazuo, IWATSURU, Motoharu

Journal:

Biological & Pharmaceutical Bulletin

Année:

1996

Fichier:

PDF, 834 KB

1996

36

Studies on Decomposition and Stabilization of Drugs in Solution. XIV. Stabilization of Methantheline Bromide and Choline Derivatives in Aqueous Solution by Surface-active Agents.

Nogami, Hisashi, Awazu, Shoji, Iwatsuru, Motoharu

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1963

Fichier:

PDF, 543 KB

1963

37

The Stabilization Mechanism of Acylcholinesters in Aqueous Solution by Sodium Lauryl Sulfate

NOGAMI, HISASHI, HASEGAWA, JUN, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1970

Fichier:

PDF, 646 KB

1970

38

Ammonia adducts of barbiturates and their application to particle size reduction.

SEKIGUCHI, KEIJI, TSUDA, YASUYUKI, KANKE, MOTOKO, SUZUKI, ETSUKO, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1978

Fichier:

PDF, 1.39 MB

1978

39

Determination of particle size and its distribution of drug powder by dissolution rate measurements.

SEKIGUCHI, KEIJI, IWATSURU, MOTOHARU, SHIROTANI, KENICHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1978

Fichier:

PDF, 649 KB

1978

40

Classification of drugs on the basis of bilirubin-displacing effect on human serum albumin.

MARUYAMA, KAZUO, HARADA, SETSUKO, NISHIGORI, HIDEO, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1984

Fichier:

PDF, 822 KB

1984

41

Effects of fatty acid on the specific drug-binding sites of human serum albumin.

MARUYAMA, KAZUO, AWAZU, SHOJI, NISHIGORI, HIDEO, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1986

Fichier:

PDF, 894 KB

1986

42

Application of double-reciprocal plot between the shift-length of absorption maxima of solubilized alkylparabens and sodium dodecyl sulfate concentration to the determination of the distribution parameter.

IWATSURU, MOTOHARU, SHIMIZU, KIYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1986

Fichier:

PDF, 431 KB

1986

43

Measurement of the distribution parameter in solubilized systems. Application of the derivative spectrum method to alkylparabens solubilized with sodium dodecyl sulfate.

IWATSURU, MOTOHARU, SHIMIZU, KIYOSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1986

Fichier:

PDF, 603 KB

1986

44

Measurement of the critical micelle concentration of nonionic surfactants by the first derivative absorption spectrum method.

SHIMIZU, KIYOSHI, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1988

Langue:

english

Fichier:

PDF, 644 KB

english, 1988

45

Measurement of the distribution parameter in solubilized systems. II. Measurement of the distribution parameter of alkylparabens and alkyl gallates in ionic and nonionic surfactant solutions.

SHIMIZU, KIYOSHI, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1988

Fichier:

PDF, 614 KB

1988

46

Measurement of the critical micelle concentration of nonionic-nonionic mixed surfactant systems by the first derivative absorption spectrum method and the region of cooperative micelles.

SHIMIZU, Kiyoshi, IWATSURU, Motoharu

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1990

Fichier:

PDF, 776 KB

1990

47

Application of the First Derivative Absorption Spectrum-Shift-Length Method to the Simultaneous Determination of Binary Mixture.

SHIMIZU, Kiyoshi, MOTOYAMA, Yoshinori, IWATSURU, Motoharu

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1992

Fichier:

PDF, 626 KB

1992

48

Location of naphthol yellow-S binding site on bovine serum albumin.

IWATSURU, MOTOHARU, NISHIGORI, HIDEO, MARUYAMA, KAZUO

Journal:

Journal of Pharmacobio-Dynamics

Année:

1981

Fichier:

PDF, 870 KB

1981

49

Location of drug binding sites on human serum albumin.

MARUYAMA, KAZUO, NISHIGORI, HIDEO, IWATSURU, MOTOHARU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1986

Fichier:

PDF, 517 KB

1986

50

The classification of drugs on the basis of the drug-binding site on human serum albumin.

IWATSURU, MOTOHARU, NISHIGORI, HIDEO, MARUYAMA, KAZUO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1982

Fichier:

PDF, 562 KB

1982